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KMID : 0032220110230040544
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Annals of Dermatology
2011 Volume.23 No. 4 p.544 ~ p.547
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Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
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Ha You-Jin
Han You-Jin
Choi You-Won
Myung Ki-Bum
Choi Hae-Young
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Abstract
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A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil®, Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine.
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KEYWORD
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Cutaneous leukocytoclastic vasculitis, Drug induced vasculitis, Sibutramine
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